Aminocaproic acid
SIAL/PHR1224 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: 6-Aminocaproic acid; ε-Aminocaproic acid; 6-Aminohexanoic acid; EACA
CAS Number: 60-32-2
Empirical Formula (Hill Notation): C6H13NO2
Molecular Weight: 131.17
EC Number: 200-469-3
MDL Number: MFCD00008238
Linear Formula: H2N(CH2)5CO2H
Product Type: Chemical
| agency | traceable to Ph. Eur. A0420000 |
| traceable to USP 1021000 | |
| API family | aminocaproic acid |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C6H13NO2/c7-5-3-1-2-4- |
| InChI key | SLXKOJJOQWFEFD-UHFFFAOYSA |
| mp | 207-209 °C (dec.) (lit.) |
| Quality Level | 300  |
| SMILES string | NCCCCCC(O)=O |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | Aminocaproic acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by fluorimetry and in bulk and injectable forms using colorimetric method. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Biochem/physiol Actions: | Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA9036 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Aminocaproic acid is a synthetic inhibitor of fibrinolysis and is utilized for the control of excessive bleeding in patients with amegakaryocytic thrombocytopenia. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 207-209 °C (dec.) (lit.) |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |