Biotin
SIAL/PHR1233 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: D-Biotin; Bios II; Coenzyme R; Vitamin B7; Vitamin H
CAS Number: 58-85-5
Empirical Formula (Hill Notation): C10H16N2O3S
Molecular Weight: 244.31
EC Number: 200-399-3
MDL Number: MFCD00005541
Linear Formula: C10H16N2O3S
Product Type: Chemical
| agency | traceable to Ph. Eur. B1116000 |
| traceable to USP 1071508 | |
| API family | biotin |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C10H16N2O3S/c13-8(14)4 |
| InChI key | YBJHBAHKTGYVGT-ZKWXMUAHSA |
| mp | 231-233 °C (lit.) |
| Quality Level | 300  |
| SMILES string | [H][C@]12CS[C@@H](CCCCC(O |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | Biotin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical preparations using a bio-sensing system and chromatography techniques. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC0265 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Biotin is a water-soluble vitamin, essential for amino acids and carbohydrates metabolism. It is involved in de novo synthesis of purine nucleotides and plays a role in gene expression and DNA replication. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 231-233 °C (lit.) |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |