Synonym: Chloroquine diphosphate salt; N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt
CAS Number: 50-63-5
Empirical Formula (Hill Notation): C18H26ClN3 · 2H3PO4
Molecular Weight: 515.86
EC Number: 200-055-2
MDL Number: MFCD00069852
Linear Formula: C18H26ClN3 · 2H3PO4
Product Type: Chemical
| agency |
BP |
| |
EP |
| |
traceable to USP 1118000 |
| |
USP |
| API family |
chloroquine |
| application(s) |
pharmaceutical (small molecule) |
| biological source |
synthetic |
| CofA |
current certificate can be downloaded |
| color |
white to yellow |
| format |
neat |
| grade |
certified reference material |
| |
pharmaceutical secondary standard |
| InChI |
1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4) |
| InChI key |
QKICWELGRMTQCR-UHFFFAOYSA-N |
| mp |
200 °C (dec.) (lit.) |
| packaging |
pkg of 1 g |
| pH |
3.5-4.5 (10% in aqueous solution, pH <6.0) |
| Quality Level |
300  |
| SMILES string |
OP(O)(O)=O.OP(O)(O)=O.CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12 |
| solubility |
benzene: practically insoluble |
| |
chloroform: practically insoluble |
| |
ethanol: practically insoluble |
| |
ether: practically insoluble |
| |
water: 50 g/L |
| storage condition |
protect from light |
| storage temp. |
2-8°C |
| technique(s) |
gas chromatography (GC): suitable |
| |
HPLC: suitable |
| vapor pressure |
<0.0000001 kPa ( 25 °C) |
| Analysis Note: |
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: |
Chloroquine phosphate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by thin-layer chromatography (TLC) and liquid chromatography (LC). |
| Application: |
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: |
To see an example of a Certificate of Analysis for this material enter LRAB3715 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: |
Chloroquine phosphate is a phosphate salt of chloroquine. It belongs to the class of aminoquinoline drugs utilized as antimalarials and amebicides. |
| General description: |
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: |
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Recommended products: |
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial . |
| Symbol |
 GHS07 |
| Signal word |
Warning |
| Hazard statements |
H302 |
| Hazard Codes |
Xn |
| Risk Statements |
22 |
| Safety Statements |
22-24/25 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| mp |
200 °C (dec.) (lit.) |
| Storage Temp. |
2-8°C |
| UNSPSC |
41116107 |
