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Levodopa

SIAL/PHR1271 - Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 3,4-Dihydroxy-L-phenylalanine; 3-(3,4-Dihydroxyphenyl)-L-alanine; L-3-Hydroxytyrosine; L-DOPA; Levodopa

CAS Number: 59-92-7
Empirical Formula (Hill Notation): C9H11NO4
Molecular Weight: 197.19
EC Number: 200-445-2
MDL Number: MFCD00002598
Linear Formula: (HO)2C6H3CH2CH(NH2)CO2H
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-PHR1271-500MG 500 mg
 $107.00
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agency traceable to BP 213
  traceable to Ph. Eur. L0400000
  traceable to USP 1361009
API family levodopa
application(s) pharmaceutical (small molecule)
CofA current certificate can be downloaded
format neat
grade certified reference material
  pharmaceutical secondary standard
InChI 1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1
InChI key WTDRDQBEARUVNC-LURJTMIESA-N
mp 276-278 °C (lit.)
Quality Level 300 
SMILES string N[C@@H](Cc1ccc(O)c(O)c1)C(O)=O
storage temp. 2-8°C
technique(s) gas chromatography (GC): suitable
  HPLC: suitable
Analysis Note: These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Application: Levodopa may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using flow injection spectrophotometric method and 1H nuclear magnetic resonance spectroscopy.
Application: These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Footnote: To see an example of a Certificate of Analysis for this material enter LRAC2957 in the slot below. This is an example certificate only and may not be the lot that you receive.
General description: Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Levodopa is a metabolic precursor of the neurotransmitter dopamine and is widely used in the treatment of Parkinson′s disease.
Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
mp 276-278 °C (lit.)
Storage Temp. 2-8°C
UNSPSC 41116107

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