Dequalinium chloride
SIAL/PHR1300 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: 1,1′-Decamethylenebis(4-aminoquinaldinium) dichloride
CAS Number: 522-51-0
Empirical Formula (Hill Notation): C30H40Cl2N4
Molecular Weight: 527.57
EC Number: 208-330-9
MDL Number: MFCD00063502
Linear Formula: C30H40Cl2N4
Product Type: Chemical
| agency | traceable to Ph. Eur. D0430000 |
| API family | dequalinium |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C30H38N4.2ClH/c1-23-21 |
| InChI key | LTNZEXKYNRNOGT-UHFFFAOYSA |
| mp | ≥300 °C (lit.) |
| Quality Level | 300  |
| SMILES string | [Cl-].[Cl-].Cc1cc(N)c2ccc |
| storage temp. | 2-8°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | Dequalinium chloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC). |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC3331 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Dequalinium chloride (DECA) is a cationic, lipophilic mitochondrial toxin which can act as a cyctotoxic agent on the mitochondrial membrane of specific epithelial carcinoma cells, by inhibiting the cellular energy production. It can have useful applications in cancer therapy. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | ≥300 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |