Residual Solvent - Toluene
SIAL/PHR1317 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Toluene
CAS Number: 108-88-3
Empirical Formula (Hill Notation): C7H8
Molecular Weight: 92.14
EC Number: 203-625-9
MDL Number: MFCD00008512
Linear Formula: C6H5CH3
Product Type: Chemical
| agency | traceable to USP 1601805 |
| application(s) | pharmaceutical (small molecule) |
| autoignition temp. | 997 °F |
| bp | 110-111 °C (lit.) |
| CofA | current certificate can be downloaded |
| density | 0.865 g/mL at 25 °C (lit.) |
| expl. lim. | 7 % |
| format | single component solution |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C7H8/c1-7-5-3-2-4-6-7/ |
| InChI key | YXFVVABEGXRONW-UHFFFAOYSA |
| mp | -93 °C (lit.) |
| Quality Level | 300  |
| refractive index | n |
| SMILES string | Cc1ccccc1 |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| vapor density | 3.2 (vs air) |
| vapor pressure | 22 mmHg ( 20 °C) |
| 26 mmHg ( 25 °C) |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC1709 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvent – Toluene is a certified reference material for the screening and quantification of residual solvents. This CRM is a secondary pharmaceutical reference standard and is traceable and qualified against the corresponding pharmacopeial standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Symbol |    GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H304 - H315 - H336 - H361d - H373 - H412 |
| Precautionary statements | P201 - P210 - P273 - P301 + P310 + P331 - P302 + P352 - P308 + P313 |
| Hazard Codes | F,Xn |
| Risk Statements | 63-11-38-48/20-65-67 |
| Safety Statements | 36/37-46-62 |
| RIDADR | UN1294 - class 3 - PG 2 - Toluene |
| WGK Germany | WGK 2 |
| Flash Point(F) | 39.2 °F |
| Flash Point(C) | 4.0 °C |
| bp | 110-111 °C (lit.) |
| mp | -93 °C (lit.) |
| Density | 0.865 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |