Residual Solvent - Trichloroethylene
SIAL/PHR1319 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Trichloroethylene; TCE; Trichloroethene
CAS Number: 79-01-6
Empirical Formula (Hill Notation): C2HCl3
Molecular Weight: 131.39
MDL Number: MFCD00000838
Linear Formula: ClCH=CCl2
Product Type: Chemical
agency | traceable to USP 1601827 |
application(s) | pharmaceutical (small molecule) |
autoignition temp. | 770 °F |
bp | 86.7 °C (lit.) |
CofA | current certificate can be downloaded |
density | 1.463 g/mL at 25 °C (lit.) |
format | single component solution |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C2HCl3/c3-1-2(4)5/h1H |
InChI key | XSTXAVWGXDQKEL-UHFFFAOYSA |
mp | −84.8 °C (lit.) |
Quality Level | 300 ![]() |
refractive index | n |
SMILES string | ClC=C(Cl)Cl |
storage temp. | 2-30°C |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable | |
vapor density | 4.5 (vs air) |
vapor pressure | 61 mmHg ( 20 °C) |
Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA0678 in the slot below. This is an example certificate only and may not be the lot that you receive. |
General description: | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvent - Trichloroethylene belongs to the group of class 2 residual solvents. The use of class 2 solvents should be limited in drug substances, excipients, dietary ingredients, and official products because of the inherent toxicities of these residual solvents. Trichloroethylene is a volatile and chlorinated organic compound, which finds applications as a solvent and greasing agent. |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Symbol | ![]() |
Signal word | Danger |
Hazard statements | H350 |
Precautionary statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
Hazard Codes | T |
Risk Statements | 45 |
Safety Statements | 53-45 |
RIDADR | NA 1993 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | 188.6 °F - closed cup |
Flash Point(C) | 87 °C - closed cup |
bp | 86.7 °C (lit.) |
mp | −84.8 °C (lit.) |
Density | 1.463 g/mL at 25 °C (lit.) |
Refractive Index | n |
Storage Temp. | 2-30°C |
UNSPSC | 41116107 |