Allantoin
SIAL/PHR1364 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Allantoin; 5-Ureidohydantoin; Glyoxylic(acid) diureide
CAS Number: 97-59-6
Empirical Formula (Hill Notation): C4H6N4O3
Molecular Weight: 158.12
EC Number: 202-592-8
MDL Number: MFCD00005260
Linear Formula: C4H6N4O3
Product Type: Chemical
| agency | traceable to Ph. Eur. A0349000 |
| traceable to USP 1012939 | |
| API family | allantoin |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C4H6N4O3/c5-3(10)6-1-2 |
| InChI key | POJWUDADGALRAB-UHFFFAOYSA |
| mp | 230 °C (dec.) (lit.) |
| Quality Level | 300  |
| SMILES string | NC(=O)NC1NC(=O)NC1=O |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | Allantoin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Biochem/physiol Actions: | Purine metabolite via the uric acid pathway. Uric acid also reacts with free radicals to produce allantoin, thus allantoin may be a useful biomarker for oxidative stress. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA1468 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Allantoin, the final catabolic product of purines in mammals, is a highly polar and amphoteric substance. Allantoin is mainly used for skin protection as the drug promotes cell proliferation and wound healing. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Recommended products: | Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial . |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 230 °C (dec.) (lit.) |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |