Dibutyl Phthalate
SIAL/PHR1366 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Dibutyl phthalate; n-Butyl phthalate; DBP; Phthalic acid dibutyl ester
CAS Number: 84-74-2
Empirical Formula (Hill Notation): C16H22O4
Molecular Weight: 278.34
EC Number: 201-557-4
MDL Number: MFCD00009441
Linear Formula: C6H4-1,2-[CO2(CH2)3CH3]2
Product Type: Chemical
| agency | traceable to Ph. Eur. D1010000 |
| traceable to USP 1187080 | |
| API family | dibutyl phthalate |
| application(s) | pharmaceutical (small molecule) |
| autoignition temp. | 756 °F |
| bp | 340 °C (lit.) |
| CofA | current certificate can be downloaded |
| density | 1.043 g/mL at 25 °C (lit.) |
| expl. lim. | 0.47 %, 236 °F |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C16H22O4/c1-3-5-11-19- |
| InChI key | DOIRQSBPFJWKBE-UHFFFAOYSA |
| mp | −35 °C (lit.) |
| packaging | pkg of 1 g |
| Quality Level | 300  |
| refractive index | n |
| SMILES string | CCCCOC(=O)c1ccccc1C(=O)OC |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| vapor density | 9.6 (vs air) |
| vapor pressure | 1 mmHg ( 147 °C) |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: | Dibutyl Phthalate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and dietary supplements by chromatography. |
| Application: | Plasticizer |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA1470 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Dibutyl Phthalate is a diester of phthalate, commonly synthesized by the condensation of the carboxy groups of phthalic acid with two molecules of 1-butanol. It is used as a plasticizer and film coating agent in solid pharmaceutical dosage forms. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Symbol |   GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H360FD - H410 |
| Precautionary statements | P201 - P273 - P308 + P313 |
| Hazard Codes | T,N |
| Risk Statements | 61-50-62 |
| Safety Statements | 53-45-61 |
| RIDADR | UN 3082 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 339.8 °F |
| Flash Point(C) | 171 °C |
| bp | 340 °C (lit.) |
| mp | −35 °C (lit.) |
| Density | 1.043 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |