Methanol
SIAL/PHR1372 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Methanol; Methyl alcohol
CAS Number: 67-56-1
Empirical Formula (Hill Notation): CH4O
Molecular Weight: 32.04
EC Number: 200-659-6
MDL Number: MFCD00004595
Linear Formula: CH3OH
Product Type: Chemical
| agency | traceable to USP 1424109 |
| application(s) | pharmaceutical (small molecule) |
| autoignition temp. | 725 °F |
| bp | 64.7 °C (lit.) |
| CofA | current certificate can be downloaded |
| density | 0.791 g/mL at 25 °C (lit.) |
| expl. lim. | 36 % |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/CH4O/c1-2/h2H,1H3 |
| InChI key | OKKJLVBELUTLKV-UHFFFAOYSA |
| mp | −98 °C (lit.) |
| Quality Level | 300  |
| refractive index | n |
| SMILES string | CO |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| vapor density | 1.11 (vs air) |
| vapor pressure | 410 mmHg ( 50 °C) |
| 97.68 mmHg ( 20 °C) |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAB7353 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Methanol is a widely used polar organic solvent in chemistry, biochemistry, and molecular biology. It is a common solvent in HPLC and mass spectrometry (MS) of small molecules and of biomolecules such as oligonucleotides and proteins. Methanol is also utilized in high performance capillary electrophoresis. Industrial applications of methanol include the manufacture of formaldehyde and methyl esters of organic and inorganic acids. Methanol is used as a solvent and solvent adjuvant for polymers, and as a softening agent for pyroxylin plastics. |
| Recommended products: | Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial . |
| Symbol |    GHS02,GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H301 + H311 + H331 - H370 |
| Precautionary statements | P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311 |
| Hazard Codes | F,T |
| Risk Statements | 11-23/24/25-39/23/24/25 |
| Safety Statements | 7-16-36/37-45 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol |
| WGK Germany | WGK 2 |
| Flash Point(F) | 49.5 °F - closed cup |
| Flash Point(C) | 9.7 °C - closed cup |
| bp | 64.7 °C (lit.) |
| mp | −98 °C (lit.) |
| Density | 0.791 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |