Synonym: Loratadine; 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester; Loratidine
CAS Number: 79794-75-5
Empirical Formula (Hill Notation): C22H23N2O2Cl
Molecular Weight: 382.88
MDL Number: MFCD00672869
Linear Formula: C22H23N2O2Cl
Product Type: Chemical
| agency |
traceable to BP 874 |
| |
traceable to Ph. Eur. Y0000688 |
| |
traceable to USP 1370270 |
| API family |
loratadine |
| application(s) |
pharmaceutical (small molecule) |
| CofA |
current certificate can be downloaded |
| format |
neat |
| grade |
certified reference material |
| |
pharmaceutical secondary standard |
| InChI |
1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3 |
| InChI key |
JCCNYMKQOSZNPW-UHFFFAOYSA-N |
| Quality Level |
300  |
| SMILES string |
CCOC(=O)N1CCC(CC1)=C2/c3ccc(Cl)cc3CCc4cccnc24 |
| storage temp. |
2-30°C |
| technique(s) |
gas chromatography (GC): suitable |
| |
HPLC: suitable |
| Analysis Note: |
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: |
Loratadine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique. |
| Application: |
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Biochem/physiol Actions: |
Non-sedating histamine H1-receptor antagonist. |
| Footnote: |
To see an example of a Certificate of Analysis for this material enter LRAC3785 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: |
Loratadine belongs to the class of H1-antihistamine drugs, with non-sedating properties, and is widely used in the treatment of allergies. |
| Other Notes: |
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 2 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Storage Temp. |
2-30°C |
| UNSPSC |
41116107 |
