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Atropine Sulfate

SIAL/PHR1379 - Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Atropine sulfate salt monohydrate; α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester; Tropine tropate

CAS Number: 5908-99-6
Empirical Formula (Hill Notation): C34H46N2O6 · H2O4S · H2O
Molecular Weight: 694.83
EC Number: 200-235-0
MDL Number: MFCD00074815
Linear Formula: (C17H23NO3)2 · H2SO4 · H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-PHR1379-1G 1 g
 $116.00
1/EA		 Add To Favorites

 

agency traceable to BP 23
  traceable to Ph. Eur. A1400000
  traceable to USP 1045009
API family atropine
application(s) pharmaceutical (small molecule)
CofA current certificate can be downloaded
format neat
grade certified reference material
  pharmaceutical secondary standard
InChI 1S/2C17H23NO3.H2O4S.H2O/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4;/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4);1H2/t2*13-,14+,15+,16?;;
InChI key JPKKQJKQTPNWTR-CHYDPLAESA-N
mp 189-192 °C (A) (lit.)
Quality Level 300 
SMILES string O.OS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3.CN4[C@H]5CC[C@@H]4C[C@@H](C5)OC(=O)C(CO)c6ccccc6
storage temp. 2-8°C
technique(s) gas chromatography (GC): suitable
  HPLC: suitable
Application: Atropine Sulfate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by electrophoresis and chromatography techniques.
Application: These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions: Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.
Footnote: To see an example of a Certificate of Analysis for this material enter LRAC4087 in the slot below. This is an example certificate only and may not be the lot that you receive.
General description: Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Atropine Sulfate is an alkaloid extracted from belladonna herb. It is a cholinergic drug, administered as an anti-arrhythmic medicine.
mp 189-192 °C (A) (lit.)
Storage Temp. 2-8°C
UNSPSC 41116107

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