Adenine
SIAL/PHR1383 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Adenine; 6-Aminopurine; Vitamin B4
CAS Number: 73-24-5
Empirical Formula (Hill Notation): C5H5N5
Molecular Weight: 135.13
EC Number: 200-796-1
MDL Number: MFCD00041790
Linear Formula: C5H5N5
Product Type: Chemical
| agency | traceable to Ph. Eur. A0230000 |
| traceable to USP 1012101 | |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C5H5N5/c6-4-3-5(9-1-7- |
| InChI key | GFFGJBXGBJISGV-UHFFFAOYSA |
| mp | >360 °C (lit.) |
| Quality Level | 300  |
| SMILES string | Nc1ncnc2[nH]cnc12 |
| storage temp. | 2-8°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | Adenine may be used as a pharmaceutical reference standard for the quantification of the analyte in infusion solutions using high-performance liquid chromatography technique and capillary electrophoresis. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| General description: | Adenine is a purine nucleobase with a wide range of chemical and biochemical roles in vivo and in vitro. It is a regulatory molecule and a component of DNA, RNA, cofactors (NAD, FAD) and signaling molecules (cAMP). |
| General description: | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 + P330 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 26-36 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | >360 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |