Irbesartan
SIAL/PHR1443 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: 2-Butyl-3-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
CAS Number: 138402-11-6
Empirical Formula (Hill Notation): C25H28N6O
Molecular Weight: 428.53
MDL Number: MFCD00864464
Linear Formula: C25H28N6O
Product Type: Chemical
| agency | traceable to BP 1093 |
| traceable to Ph. Eur. Y0001166 | |
| traceable to USP 1347700 | |
| API family | irbesartan |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C25H28N6O/c1-2-3-10-22 |
| InChI key | YOSHYTLCDANDAN-UHFFFAOYSA |
| packaging | pkg of 1 g |
| Quality Level | 300  |
| SMILES string | CCCCC1=NC2(CCCC2)C(=O)N1C |
| storage temp. | 2-8°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: | Irbesartan may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and combined dosage forms by chromatography and spectrophotometric techniques. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC2897 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Irbesartan is a potent, long-acting “sartan” class, nonpeptide, angiotensin II receptor antagonist utilized for the management of hypertension as well as heart failure in clinical patients. It shows high selectivity for the AT1 subtype (angiotensin I), and effectively reduces the probabilities of cardiac failure, myocardial infarction, sudden death, etc. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |