Pilocarpine Nitrate
SIAL/PHR1494 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Pilocarpine nitrate salt
CAS Number: 148-72-1
Empirical Formula (Hill Notation): C11H16N2O2 · HNO3
Molecular Weight: 271.27
EC Number: 205-723-7
MDL Number: MFCD00078497
Linear Formula: C11H16N2O2 · HNO3
Product Type: Chemical
agency | traceable to BP 503 |
traceable to Ph. Eur. P1700000 | |
traceable to USP 1539009 | |
API family | pilocarpine |
application(s) | pharmaceutical (small molecule) |
CofA | current certificate can be downloaded |
format | neat |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C11H16N2O2.HNO3/c1-3-1 |
InChI key | PRZXEPJJHQYOGF-GNAZCLTHSA |
packaging | pkg of 500 mg |
Quality Level | 300 |
SMILES string | O[N+]([O-])=O.CC[C@H]1[C@ |
storage temp. | 2-30°C |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
Biochem/physiol Actions: | Nonselective muscarinic acetylcholine receptor agonist; used to produce an experimental model of epilepsy. |
Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA3042 in the slot below. This is an example certificate only and may not be the lot that you receive. |
General description: | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Pilocarpine Nitrate is a naturally occurring cholinomimetic drug, exhibiting nicotinic and muscarinic properties. It is widely used for controlling intraocular pressure in glaucoma, immediate relief of mydriasis, and to reverse mydriasis caused by cycloplegic agents. |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Symbol | GHS03,GHS06 |
Signal word | Danger |
Hazard statements | H272 - H302 - H330 |
Precautionary statements | P210 - P220 - P260 - P264 - P301 + P312 - P304 + P340 + P310 |
Hazard Codes | T+ |
Risk Statements | 26/28 |
Safety Statements | 25-45 |
RIDADR | UN 2811 6.1 / PGII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-30°C |
UNSPSC | 41116107 |