Acetaminophen Related Compound D
SIAL/PHR1530 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Acetanilide; Acetanilide; N-Phenylacetamide
CAS Number: 103-84-4
Empirical Formula (Hill Notation): C8H9NO
Molecular Weight: 135.16
EC Number: 203-150-7
MDL Number: MFCD00008674
Linear Formula: CH3CONHC6H5
Product Type: Chemical
| agency | traceable to USP 1003042 |
| application(s) | pharmaceutical (small molecule) |
| autoignition temp. | 1004 °F |
| bp | 304 °C (lit.) |
| CofA | current certificate can be downloaded |
| description | API family: acetaminophen |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C8H9NO/c1-7(10)9-8-5-3 |
| InChI key | FZERHIULMFGESH-UHFFFAOYSA |
| mp | 113-115 °C (lit.) |
| packaging | pkg of 200 mg |
| Quality Level | 100  |
| 300 |
|
| SMILES string | CC(=O)Nc1ccccc1 |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| vapor density | 4.65 (vs air) |
| vapor pressure | 1 mmHg ( 114 °C) |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: | This pharmaceutical secondary standard can also be used as follows: • Detection and quantification of paracetamol, phenylephrine hydrochloride, and paracetamol impurities in pharmaceutical formulations using four chemometric-based spectrophotometric methods • Simultaneous determination of paracetamol and phenylephrine hydrochloride in the presence of paracetamol-related impurities using capillary zone electrophoresis (CZE) in their combined tablet forms |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA3648 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. It is an impurity of the widely used antipyretic and analgesic drug acetaminophen, also known as paracetamol. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301 + P312 + P330 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 321.8 °F - closed cup |
| Flash Point(C) | 161 °C - closed cup |
| bp | 304 °C (lit.) |
| mp | 113-115 °C (lit.) |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |