Oxytetracycline
SIAL/PHR1537 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Oxytetracycline dihydrate; OTC
CAS Number: 6153-64-6
Empirical Formula (Hill Notation): C22H24N2O9 · 2H2O
Molecular Weight: 496.46
EC Number: 201-212-8
MDL Number: MFCD00151234
Linear Formula: C22H24N2O9 · 2H2O
Product Type: Chemical
| agency | traceable to BP 782 |
| traceable to Ph. Eur. Y0001896 | |
| traceable to USP 1491004 | |
| API family | oxytetracycline |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C22H24N2O9.H2O/c1-21(3 |
| InChI key | IBZHEBHGZFICKS-IFLJXUKPSA |
| packaging | pkg of 1 g |
| Quality Level | 300  |
| SMILES string | O.[H][C@@]12[C@@H](O)[C@@ |
| storage temp. | -10 to -25°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: | Oxytetracycline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrofluorimetry techniques. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Biochem/physiol Actions: | Antibiotic produced by Streptomyces rimosus. Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. Mode of Resistance: Active efflux, ribosome protection, tetracycline inactivation. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC0364 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Oxytetracycline is a broad-spectrum antibiotic which finds a wide use in veterinary medicine because of its potential to inhibit the protein synthesis in gram-positive and gram-negative bacteria. It can be used on animal species like cattle, sheep, goats and pigs. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Symbol |   GHS08,GHS09 |
| Signal word | Warning |
| Hazard statements | H361d - H411 |
| Precautionary statements | P201 - P202 - P273 - P280 - P308 + P313 - P391 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | -10 to -25°C |
| UNSPSC | 41116107 |