Pyridine
SIAL/PHR1558 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Pyridine
CAS Number: 110-86-1
Empirical Formula (Hill Notation): C5H5N
Molecular Weight: 79.10
EC Number: 203-809-9
MDL Number: MFCD00011732
Linear Formula: C5H5N
Product Type: Chemical
| agency | traceable to USP 1601747 |
| application(s) | pharmaceutical (small molecule) |
| autoignition temp. | 899 °F |
| bp | 115 °C (lit.) |
| CofA | current certificate can be downloaded |
| density | 0.978 g/mL at 25 °C (lit.) |
| expl. lim. | 12.4 % |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C5H5N/c1-2-4-6-5-3-1/h |
| InChI key | JUJWROOIHBZHMG-UHFFFAOYSA |
| mp | −42 °C (lit.) |
| packaging | ampule of 3x1.2 mL each |
| Quality Level | 300  |
| refractive index | n |
| SMILES string | C1=CN=CC=C1 |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| vapor density | 2.72 (vs air) |
| vapor pressure | 10 mmHg ( 13.2 °C) |
| 20 mmHg ( 25 °C) |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC0263 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Pyridine is a heterocyclic aromatic compound that is a commonly used solvent in organic and inorganic chemistry. Its weakly basic nature allows it to act as a proton acceptor in acid base reactions, and to form salts with strong acids. In the acylation of alcohols, pyridine can act as a nucleophilic catalyst. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Symbol |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225 - H302 + H312 + H332 - H315 - H319 |
| Precautionary statements | P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-20/21/22-36/38-52 |
| Safety Statements | 26-28 |
| RIDADR | UN1282 - class 3 - PG 2 - Pyridine |
| WGK Germany | WGK 2 |
| Flash Point(F) | 68.0 °F - closed cup |
| Flash Point(C) | 20 °C - closed cup |
| bp | 115 °C (lit.) |
| mp | −42 °C (lit.) |
| Density | 0.978 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |