Levocarnitine
SIAL/PHR1569 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: L-Carnitine inner salt; (−)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate; Vitamin BT
CAS Number: 541-15-1
Empirical Formula (Hill Notation): C7H15NO3
Molecular Weight: 161.20
EC Number: 208-768-0
MDL Number: MFCD00038747
Linear Formula: (CH3)3N+CH2CH(OH)CH2COO-
Product Type: Chemical
| agency | traceable to Ph. Eur. L0399900 |
| traceable to USP 1359903 | |
| API family | levocarnitine |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C7H15NO3/c1-8(2,3)5-6( |
| InChI key | PHIQHXFUZVPYII-ZCFIWIBFSA |
| mp | 197-212 °C (lit.) |
| packaging | pkg of 1 g |
| Quality Level | 300  |
| SMILES string | C[N+](C)(C)C[C@H](O)CC([O |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Biochem/physiol Actions: | Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAB7787 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Levocarnitine is a naturally available compound that plays a significant role in fatty acid oxidation and energy production in the human body. It is majorly found in skeletal and cardiac muscles of mammals and facilitates the transport of long chain fatty acids into mitochondria. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Recommended products: | Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial . |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 197-212 °C (lit.) |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |