Dehydroacetic acid
SIAL/PHR1582 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Dehydroacetic acid; 2-
CAS Number: 520-45-6
Empirical Formula (Hill Notation): C8H8O4
Molecular Weight: 168.15
EC Number: 208-293-9
MDL Number: MFCD00066709
Linear Formula: C8H8O4
Product Type: Chemical
| agency | traceable to USP 1166309 |
| API family | dehydroacetic acid |
| application(s) | pharmaceutical (small molecule) |
| bp | 270 °C (lit.) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C8H8O4/c1-4-3-6(10)7(5 |
| InChI key | PGRHXDWITVMQBC-UHFFFAOYSA |
| mp | 111-113 °C (lit.) |
| packaging | pkg of 1 g |
| Quality Level | 300  |
| SMILES string | CC(=O)C1C(=O)OC(C)=CC1=O |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: | Dehydroacetic acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical, food and cosmetic formulations by chromatography. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA4498 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Dehydroacetic acid is a pyrone derivative, that is typically synthesized by the base-catalyzed dimerization of diketene. It is used as a preservative in pharmaceutical, food and cosmetic products. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264 - P270 - P301 + P312 - P501 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 314.6 °F |
| Flash Point(C) | 157 °C |
| bp | 270 °C (lit.) |
| mp | 111-113 °C (lit.) |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |