Synonym: Megestrol acetate; 17α-Acetoxy-6-methyl-4,6-pregnadiene-3,20-dione; 17α-Hydroxy-6-methyl-4,6-pregnadiene-3,20-dione 17-acetate; 17α-Hydroxy-6-methyl-6-dehydroprogesterone 17-acetate; Megestrol 17-acetate
CAS Number: 595-33-5
Empirical Formula (Hill Notation): C24H32O4
Molecular Weight: 384.51
EC Number: 209-864-5
MDL Number: MFCD00056470
Linear Formula: C24H32O4
Product Type: Chemical
| agency |
traceable to BP 223 |
| |
traceable to Ph. Eur. Y0001514 |
| |
traceable to USP 1379106 |
| application(s) |
pharmaceutical (small molecule) |
| CofA |
current certificate can be downloaded |
| format |
neat |
| grade |
certified reference material |
| |
pharmaceutical secondary standard |
| InChI |
1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h12-13,18-20H,6-11H2,1-5H3/t18-,19+,20+,22-,23+,24+/m1/s1 |
| InChI key |
RQZAXGRLVPAYTJ-GQFGMJRRSA-N |
| packaging |
pkg of 1 g |
| Quality Level |
300  |
| SMILES string |
[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@]3(OC(C)=O)C(C)=O)[C@]1([H])C=C(C)C4=CC(=O)CC[C@]24C |
| storage temp. |
2-8°C |
| technique(s) |
gas chromatography (GC): suitable |
| |
HPLC: suitable |
| Application: |
Megestrol Acetate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations, oral contraceptives and suspensions by chromatography techniques. |
| Application: |
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: |
To see an example of a Certificate of Analysis for this material enter LRAA4562 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: |
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Megestrol Acetate is a progestogen drug indicated for the palliative treatment of endometrial carcinoma and breast cancer. The administration of the drug is usually done orally as a solid dosage form. |
| Symbol |
 GHS08 |
| Signal word |
Warning |
| Hazard statements |
H351 - H373 |
| Precautionary statements |
P201 - P308 + P313 |
| Hazard Codes |
Xn |
| Risk Statements |
40-48 |
| Safety Statements |
22-24/25 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Storage Temp. |
2-8°C |
| UNSPSC |
41116107 |
