Donepezil Hydrochloride

SIAL/PHR1584 - Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Donepezil hydrochloride; (±)-2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride; 2,3-Dihydro-5,6-dimethoxy-2-{[1-(phenylmethyl)-4-piperidinyl]methyl}-1H-inden-1-one

CAS Number: 120011-70-3
Empirical Formula (Hill Notation): C₂₄H₂₉NO₃ · HCl
Molecular Weight: 415.95
Linear Formula: C₂₄H₂₉NO₃ · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-PHR1584-1G	1 g	$412.00 1/EA	Add To Favorites

This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

Properties
Descriptions
Safety Info.
Basic Data

agency	traceable to USP 1224981
API family	donepezil
application(s)	pharmaceutical (small molecule)
CofA	current certificate can be downloaded
format	neat
grade	certified reference material
	pharmaceutical secondary standard
InChI	1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H
InChI key	XWAIAVWHZJNZQQ-UHFFFAOYSA-N
packaging	pkg of 1 g
Quality Level	300
SMILES string	[Cl-].N2(CCC(CC2)CC3Cc4c(cc(c(c4)OC)OC)C3=O)Cc1ccccc1.[H+]
storage temp.	2-30°C
technique(s)	gas chromatography (GC): suitable
	HPLC: suitable

Application:	Donepezil Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and plasma samples by various chromatography techniques.
Application:	These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description:	Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Donepezil Hydrochloride is known as a selective, reversible inhibitor of acetylcholinesterase enzyme. It exhibits therapeutic effect by raising the acetylcholine concentrations and improving the cholinergic function. It can be used in the treatment of mild to moderate dementia of the Alzheimer′s type.
Other Notes:	To see an example of a Certificate of Analysis for this material enter LRAB3756 in the slot below. This is an example certificate only and may not be the lot that you receive.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	2-30°C
UNSPSC	41116107

To Order From a Quote