Thimerosal

SIAL/PHR1587 - Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Thimerosal; 2-(Ethylmercuriomercapto)benzoic acid sodium salt; Ethylmercurithiosalicylic acid sodium salt; Mercury-([o-carboxyphenyl]thio)ethyl sodium salt; Sodium ethylmercurithiosalicylate

CAS Number: 54-64-8
Empirical Formula (Hill Notation): C₉H₉HgNaO₂S
Molecular Weight: 404.81
EC Number: 200-210-4
MDL Number: MFCD00013062
Linear Formula: 2-(C₂H₅HgS)C₆H₄CO₂Na
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-PHR1587-1G	1 g	$251.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	traceable to Ph. Eur. Y0000109
	traceable to USP 1659000
API family	thimerosal
application(s)	pharmaceutical (small molecule)
CofA	current certificate can be downloaded
format	neat
grade	certified reference material
	pharmaceutical secondary standard
InChI	1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
InChI key	RTKIYNMVFMVABJ-UHFFFAOYSA-L
mp	234-237 °C (dec.) (lit.)
packaging	pkg of 1 g
Quality Level	300
SMILES string	[Na+].CC[Hg]Sc1ccccc1C([O-])=O
storage temp.	2-30°C
technique(s)	gas chromatography (GC): suitable
	HPLC: suitable

Analysis Note:	These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application:	These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Application:	Thimerosal may be used as a pharmaceutical reference standard for the quantification of the analyte in ophthalmic solutions using spectrophotometric technique.
Biochem/physiol Actions:	Thimerosal is a sulfhydryl (thiol) oxidizing reagent capable of inhibiting a wide range of sulfhydryl-dependent enzymes and proteins such as PI3-kinase-dependent methionine synthase, glutamate transport receptors, and Na⁺+K⁺ dependent ATPases.
Disclaimer:	For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.
General description:	Thimerosal belongs to the group of alkyl mercury compounds. Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Other Notes:	This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Other Notes:	To see an example of a Certificate of Analysis for this material enter LRAA6959 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Symbol	GHS06,GHS08,GHS09
Signal word	Danger
Hazard statements	H300 + H310 + H330 - H373 - H410
Precautionary statements	P262 - P273 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310
Hazard Codes	T+,N
Risk Statements	26/27/28-33-50/53
Safety Statements	13-28-36-45-60-61
RIDADR	UN 2025 6.1 / PGIII
WGK Germany	WGK 3
Flash Point(F)	482.0 °F - closed cup
Flash Point(C)	250 °C - closed cup

mp	234-237 °C (dec.) (lit.)
Storage Temp.	2-30°C
UNSPSC	41116107

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