Losartan Potassium
SIAL/PHR1602 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Losartan potassium; 2-
CAS Number: 124750-99-8
Empirical Formula (Hill Notation): C22H22ClKN6O
Molecular Weight: 461.00
MDL Number: MFCD02092704
Linear Formula: C22H22ClKN6O
Product Type: Chemical
agency | traceable to BP 867 |
traceable to Ph. Eur. Y0001062 | |
traceable to USP 1370462 | |
application(s) | pharmaceutical (small molecule) |
CofA | current certificate can be downloaded |
format | neat |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C22H22ClN6O.K/c1-2-3-8 |
InChI key | OXCMYAYHXIHQOA-UHFFFAOYSA |
packaging | pkg of 1 g |
Quality Level | 300 ![]() |
SMILES string | CCCCc1nc(Cl)c(CO)n1Cc2ccc |
storage temp. | 2-30°C |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Application: | Losartan Potassium may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques and spectrophotometric technique. |
Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
Biochem/physiol Actions: | Losartan potassium is an orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist. Losartan potassium is used for treatment of hypertension. |
Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC0141 in the slot below. This is an example certificate only and may not be the lot that you receive. |
General description: | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Losartan Potassium is a novel class of orally active, non-peptide angiotensin II (type AT1) receptor antagonist drug that can be used in the remedy of hypertension. It exhibits superior activity than many other peptide receptor antagonist drugs and angiotensin converting enzyme (ACE) inhibitors owing to the high specificity, selectivity, and tolerability. |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-30°C |
UNSPSC | 41116107 |