Hydrocortisone Acetate

SIAL/PHR1606 - Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Hydrocortisone 21-acetate; 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-acetate; 17-α-Hydroxycorticosterone acetate; 17-Hydroxycorticosterone 21-acetate; 21-Acetoxy-4-pregnene-11β,17α-diol-3,20-dione; 4-Pregnene-11β,17α,21-triol-3,20-dione 21-acetate

CAS Number: 50-03-3
Empirical Formula (Hill Notation): C₂₃H₃₂O₆
Molecular Weight: 404.50
EC Number: 200-004-4
MDL Number: MFCD00037714
Linear Formula: C₂₃H₃₂O₆
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-PHR1606-1G	1 g	$109.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	traceable to BP 584
	traceable to Ph. Eur. H1400000
	traceable to USP 1317007
API family	hydrocortisone
application(s)	pharmaceutical (small molecule)
CofA	current certificate can be downloaded
format	neat
grade	certified reference material
	pharmaceutical secondary standard
InChI	1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1
InChI key	ALEXXDVDDISNDU-JZYPGELDSA-N
mp	223 °C (dec.) (lit.)
packaging	pkg of 1 g
Quality Level	300
SMILES string	[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O
storage temp.	2-30°C
technique(s)	gas chromatography (GC): suitable
	HPLC: suitable

Analysis Note:	These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Application:	Hydrocortisone Acetate may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using reversed-phase high-performance liquid chromatography and thin layer chromatography techniques.
Application:	These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Footnote:	To see an example of a Certificate of Analysis for this material enter LRAC3177 in the slot below. This is an example certificate only and may not be the lot that you receive.
General description:	Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Hydrocortisone Acetate belongs to the class of corticosteroids, exhibiting antipruritic, anti-inflammatory and vasoconstrictive properties. It is used in the treatment of various conditions such as allergic and breathing disorders or skin conditions.
Other Notes:	This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Symbol	GHS08
Signal word	Danger
Hazard statements	H360Df - H373
Precautionary statements	P202 - P260 - P280 - P308 + P313 - P405 - P501
Hazard Codes	Xn
Risk Statements	63
Safety Statements	36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

mp	223 °C (dec.) (lit.)
Storage Temp.	2-30°C
UNSPSC	41116107

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