Valganciclovir Hydrochloride

SIAL/PHR1626 - Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Valganciclovir hydrochloride hydrate; 2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-amino-3-methylbutanoate hydrochloride hydrate; L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester, monohydrochloride hydrate

CAS Number: 175865-59-5 (anhydrous)
Empirical Formula (Hill Notation): C₁₄H₂₂N₆O₅·HCl · xH₂O
Molecular Weight: 390.82 (anhydrous basis)
Linear Formula: C₁₄H₂₂N₆O₅·HCl · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-PHR1626-1G	1 g	$173.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	traceable to USP 1708004
API family	valganciclovir
application(s)	pharmaceutical (small molecule)
CofA	current certificate can be downloaded
format	neat
grade	certified reference material
	pharmaceutical secondary standard
InChI	1S/C14H22N6O5.ClH.H2O/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22;;/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22);1H;1H2/t8?,9-;;/m0../s1
InChI key	XASVRRIYQZVANH-AHBBCRTASA-N
packaging	pkg of 1 g
Quality Level	300
SMILES string	O.Cl.CC(C)[C@H](N)C(=O)OCC(CO)OCn1cnc2C(=O)N=C(N)Nc12
storage temp.	2-8°C
technique(s)	gas chromatography (GC): suitable
	HPLC: suitable

Analysis Note:	These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Application:	These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Application:	Valganciclovir Hydrochloride may be used as a secondary pharma standard for the quantification of the analyte in pharmaceutical formulations using liquid chromatography technique.
Biochem/physiol Actions:	Valganciclovir hydrochloride hydrate is an antiviral used to treat cytomegalovirus infection. It is the prodrug of ganciclovir, a synthetic analog of 2′-deoxy-guanosine which is phosphorylated to a dGTP analog that competitively inhibits the incorporation of dGTP by viral DNA polymerase.
Footnote:	To see an example of a Certificate of Analysis for this material enter LRAA5295 in the slot below. This is an example certificate only and may not be the lot that you receive.
General description:	Valganciclovir Hydrochloride is the L-valyl ester of ganciclovir and an antiviral drug, widely used to treat cytomegalovirus infections. Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
Other Notes:	This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	2-8°C
UNSPSC	41116107

To Order From a Quote