Ropinirole Hydrochloride
SIAL/PHR1633 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Ropinirole hydrochloride; 4-
CAS Number: 91374-20-8
Empirical Formula (Hill Notation): C16H24N2O · HCl
Molecular Weight: 296.84
MDL Number: MFCD01754173
Linear Formula: C16H24N2O · HCl
Product Type: Chemical
agency | traceable to Ph. Eur. Y0001773 |
traceable to USP 1605205 | |
application(s) | pharmaceutical (small molecule) |
CofA | current certificate can be downloaded |
format | neat |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C16H24N2O.ClH/c1-3-9-1 |
InChI key | XDXHAEQXIBQUEZ-UHFFFAOYSA |
packaging | pkg of 200 mg |
Quality Level | 300 |
SMILES string | Cl.CCCN(CCC)CCc1cccc2NC(= |
storage temp. | 2-30°C |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Biochem/physiol Actions: | An agonist at the D2 and D3 dopamine receptor subtypes, binding with higher affinity to D3 than to D2 or D4. It has negligible effect on D1-receptors. It has medium in vitro affinity to opioid receptors. Ropinirole is said to have virtually no affinity to 5-HT1, 5-HT2, benzodiazepine, GABA, muscarinic, α1-, α2-, and β-adrenoreceptors. Used as antiparkinsonian drug. |
Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC2959 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
General description: | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Symbol | GHS07,GHS09 |
Signal word | Warning |
Hazard statements | H302 - H400 |
Precautionary statements | P273 - P301 + P312 + P330 |
Hazard Codes | Xn,N |
Risk Statements | 22-50/53 |
Safety Statements | 36-60-61 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-30°C |
UNSPSC | 41116107 |