Azelastine Hydrochloride
SIAL/PHR1636 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Azelastine hydrochloride; 4-
CAS Number: 79307-93-0
Empirical Formula (Hill Notation): C22H24ClN3O · HCl
Molecular Weight: 418.36
MDL Number: MFCD00242783
Linear Formula: C22H24ClN3O · HCl
Product Type: Chemical
| agency | traceable to Ph. Eur. Y0000326 |
| traceable to USP 1046158 | |
| API family | azelastine |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C22H24ClN3O.ClH/c1-25- |
| InChI key | YEJAJYAHJQIWNU-UHFFFAOYSA |
| packaging | pkg of 1 g |
| Quality Level | 300  |
| SMILES string | Cl.CN1CCCC(CC1)N2N=C(Cc3c |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: | Azelastine Hydrochloride may be used as a pharmaceutical secondary reference standard for the determination of azelastine in plasma samples by manual-injection liquid chromatographic method using fluorescence detection. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Biochem/physiol Actions: | H1 histamine receptor antagonist; NF-kB activator. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA5303 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Azelastine Hydrochloride is a long-acting antiallergic and antiasthmatic drug. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |