Carbidopa
SIAL/PHR1655 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: (S)
CAS Number: 38821-49-7
Empirical Formula (Hill Notation): C10H14N2O4 · H2O
Molecular Weight: 244.24
MDL Number: MFCD00889211
Linear Formula: C10H14N2O4 · H2O
Product Type: Chemical
| agency | traceable to BP 60 |
| traceable to Ph. Eur. C0460000 | |
| traceable to USP 1095506 | |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C10H14N2O4.H2O/c1-10(1 |
| InChI key | QTAOMKOIBXZKND-PPHPATTJSA |
| packaging | pkg of 1 g |
| Quality Level | 300  |
| SMILES string | O.C[C@@](Cc1ccc(O)c(O)c1) |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: | Carbidopa may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA5756 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Carbidopa is a peripheral decarboxylase inhibitor which is often formulated with levodopa for the management of the symptoms of Parkinson′s disease. Its mode of action involves the reduction of systemic production of dopamine and minimization of undesirable effects such as nausea. Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 - H319 |
| Precautionary statements | P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313 |
| Hazard Codes | Xi |
| Risk Statements | 36 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |