Mefloquine Hydrochloride

SIAL/PHR1705 - Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Mefloquine hydrochloride; MQ; (AS)-rel-a-(2R)-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol monohydrochloride

CAS Number: 51773-92-3
Empirical Formula (Hill Notation): C₁₇H₁₇ClF₆N₂O
Molecular Weight: 414.77
EC Number: 257-412-0
MDL Number: MFCD00797519
Linear Formula: C₁₇H₁₇ClF₆N₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-PHR1705-1G	1 g	$114.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	traceable to Ph. Eur. M0253000
	traceable to USP 1379059
API family	mefloquine
application(s)	pharmaceutical (small molecule)
CofA	current certificate can be downloaded
format	neat
grade	certified reference material
	pharmaceutical secondary standard
InChI	1S/C17H16F6N2O.ClH/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11;/h3-5,8,12,15,24,26H,1-2,6-7H2;1H/t12-,15+;/m1./s1
InChI key	WESWYMRNZNDGBX-YLCXCWDSSA-N
packaging	pkg of 1 g
Quality Level	300
SMILES string	Cl[H].[H][C@@]1(CCCCN1)[C@@H](O)c2cc(nc3c(cccc23)C(F)(F)F)C(F)(F)F
storage temp.	2-30°C
technique(s)	gas chromatography (GC): suitable
	HPLC: suitable

Analysis Note:	These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Application:	Mefloquine Hydrochloride may be used as a pharmaceutical reference standard for the determination of mefloquine in pharmaceutical formulations and plasma samples by various chromatography techniques.
Application:	These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions:	Blocker of gap junction channels Cx36 and Cx50.
Footnote:	To see an example of a Certificate of Analysis for this material enter LRAC3945 in the slot below. This is an example certificate only and may not be the lot that you receive.
General description:	Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards
Other Notes:	This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P301 + P312 + P330
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	2-30°C
UNSPSC	41116107

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