Cetirizine hydrochloride Related Compound A
SIAL/PHR1710 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Cetirizine ethyl ester dihydrochloride; (RS)
CAS Number: 246870-46-2 (free base)
Empirical Formula (Hill Notation): C23H29ClN2O3 · 2HCl
Molecular Weight: 489.86
EC Number: 206-137-4
Linear Formula: C23H29ClN2O3 · 2HCl
Product Type: Chemical
| agency | traceable to USP 1102930 |
| API family | cetirizine |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C23H29ClN2O3/c1-2-29-2 |
| InChI key | ASHQTVRYHSZGQY-UHFFFAOYSA |
| packaging | pkg of 40 mg |
| Quality Level | 300  |
| storage temp. | -10 to -25°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: | Cetirizine hydrochloride has been used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry and chromatography techniques. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA7298 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Cetirizine hydrochloride Related Compound A is an impurity of cetirizine hydrochloride. Cetirizine hydrochloride is a second-generation antihistamine compound. It is a major metabolite of hydroxyzine that exhibits high specific affinity for histamine H1 receptor. It is used for the management of allergies, hay fever, angioedema, and urticaria. Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Symbol |    GHS05,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H315 - H317 - H318 - H361fd |
| Precautionary statements | P201 - P202 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | -10 to -25°C |
| UNSPSC | 41116107 |