Buprenorphine Hydrochloride
SIAL/PHR1729 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Buprenorphine hydrochloride; [5α,7α(S)]-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)4,5-epoxy-18,19-dihydo-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol hydrochloride
CAS Number: 53152-21-9
Empirical Formula (Hill Notation): C29H41NO4 · HCl
Molecular Weight: 504.10
EC Number: 258-396-8
MDL Number: MFCD00084836
Linear Formula: C29H41NO4 · HCl
Product Type: Chemical
| agency | traceable to Ph. Eur. Y0001109 |
| traceable to USP 1078700 | |
| API family | buprenorphine |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| drug control | kontrollierte Droge in Deutschland |
| USDEA Schedule III; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet | |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C29H41NO4.ClH/c1-25(2, |
| InChI key | UAIXRPCCYXNJMQ-RZIPZOSSSA |
| packaging | pkg of 50 mg |
| Quality Level | 300  |
| SMILES string | Cl[H].CO[C@]12CC[C@@]3(C[ |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available. |
| Application: | Buprenorphine Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography method. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Biochem/physiol Actions: | Agonist at ORL1 receptors; antagonist or partial agonist at μ, κ, and δ opioid receptors. |
| Biochem/physiol Actions: | Full agonist at ORL1 receptors, antagonist or partial agonist at μ, κ, and δ opioid receptors. |
| General description: | Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Buprenorphine Hydrochloride is a potent long-acting synthetic opiate analgesic. |
| Legal Information: | German Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG. English This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Other Notes: | To see an example of a Certificate of Analysis for this material enter LRAA7438 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
| Symbol |   GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H302 - H361 |
| Precautionary statements | P201 - P301 + P312 + P330 - P308 + P313 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |