Synonym: Ritonavir; 10-Hydroxy-2-methyl-5-(1-methylethyl)-1-[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic acid, 5-thiazolylmethyl ester, [5S-(5R*, 8R*, 10R*, 11R*)]; 1,3-Thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
CAS Number: 155213-67-5
Empirical Formula (Hill Notation): C37H48N6O5S2
Molecular Weight: 720.94
Linear Formula: C37H48N6O5S2
Product Type: Chemical
| agency |
BP |
| |
EP |
| |
traceable to Ph. Eur. Y0000714 |
| |
traceable to USP 1604803 |
| |
USP |
| API family |
ritonavir |
| application(s) |
pharmaceutical (small molecule) |
| biological source |
synthetic |
| CofA |
current certificate can be downloaded |
| color |
white to tan |
| form |
powder |
| format |
neat |
| grade |
certified reference material |
| |
pharmaceutical secondary standard |
| InChI |
1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1 |
| InChI key |
NCDNCNXCDXHOMX-XGKFQTDJSA-N |
| packaging |
pkg of 1 g |
| Quality Level |
300  |
| shipped in |
ambient |
| solubility |
acetonitrile: slightly soluble |
| |
ethanol: freely soluble |
| |
methanol: freely soluble |
| |
methylene chloride: freely soluble |
| |
water: practically insoluble |
| storage condition |
protect from light |
| storage temp. |
2-30°C |
| technique(s) |
gas chromatography (GC): suitable |
| |
HPLC: suitable |
| vapor pressure |
<0.0000001 kPa ( 25 °C) |
| Analysis Note: |
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: |
Ritonavir may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using chromatography techniques. |
| Application: |
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: |
To see an example of a Certificate of Analysis for this material enter LRAB9120 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: |
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
| General description: |
Ritonavir belongs to the group of protease inhibitors, which block the part of HIV called protease. Its mode of action involves binding to the protease active site and inhibiting the activity of the enzyme. |
| Other Notes: |
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Storage Temp. |
2-30°C |
| UNSPSC |
41116107 |
GHS07