Bupropion Hydrochloride Related Compound A
SIAL/PHR1752 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: 2-(tert-Butylamino)-4′-chloropropiophenone hydrochloride; 2-
CAS Number: 1049718-72-0
Empirical Formula (Hill Notation): C13H18ClNO · HCl
Molecular Weight: 276.20
Linear Formula: C13H18ClNO · HCl
Product Type: Chemical
agency | traceable to USP 1078744 |
application(s) | pharmaceutical (small molecule) |
CofA | current certificate can be downloaded |
format | neat |
grade | certified reference material |
pharmaceutical secondary standard | |
packaging | pkg of 30 mg |
Quality Level | 300 ![]() |
storage temp. | 2-8°C |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA7916 in the slot below. This is an example certificate only and may not be the lot that you receive. |
General description: | Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Bupropion hydrochloride (BUP) and its derivatives belong to a chemical class of aminoketones and are known for their antidepressant abilities. BUP selectively inhibits the neuronal reabsorption of catecholamines (noradrenalin and dopamine), has minimal effect on the recapture of indolamines (serotonin) and no inhibitory effect on monoamine oxidase. It is used as the non-nicotine pharmacological therapy for combating smoking in controlled release form. Bupropion hydrochloride (BUP) may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometric and chromatographic techniques. |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H319 |
Precautionary statements | P280 - P305 + P351 + P338 - P337 + P313 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |