Hydroxychloroquine Sulfate
SIAL/PHR1782 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Hydroxychloroquine sulfate; 7-
CAS Number: 747-36-4
Empirical Formula (Hill Notation): C18H26ClN3O · H2SO4
Molecular Weight: 433.95
EC Number: 212-019-3
MDL Number: MFCD00078203
Linear Formula: C18H26ClN3O · H2SO4
Product Type: Chemical
| agency | BP |
| EP | |
| traceable to BP 1100 | |
| traceable to USP 1327000 | |
| USP | |
| API family | hydroxychloroquine |
| application(s) | pharmaceutical (small molecule) |
| biological source | synthetic |
| CofA | current certificate can be downloaded |
| color | white to off-white |
| form | powder or crystals |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C18H26ClN3O.H2O4S/c1-3 |
| InChI key | JCBIVZZPXRZKTI-UHFFFAOYSA |
| mp | 238-241 °C |
| packaging | pkg of 1 g |
| pH | 3.5-5.5 (1% in aqueous solution, pH <6.0) |
| Quality Level | 300  |
| shipped in | ambient |
| SMILES string | OS(O)(=O)=O.CCN(CCO)CCCC( |
| solubility | chloroform: practically insoluble |
| ethanol: practically insoluble | |
| ether: practically insoluble | |
| water: soluble | |
| storage condition | protect from light |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: | Hydroxychloroquine Sulfate can be used as a pharmaceutical secondary standard for the determination of the analyte in pharmaceutical formulations, and biological samples by various analytical techniques. These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Biochem/physiol Actions: | Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor. It is used in treating malaria. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC0287 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Hydroxychloroquine Sulfate (Hydroxychloroquine Sulphate) is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug. Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 - H315 - H319 |
| Precautionary statements | P301 + P312 + P330 - P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 238-241 °C |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |