Synonym: Imipenem monohydrate; (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate; Primaxin monohydrate; Tienam monohydrate
CAS Number: 74431-23-5
Empirical Formula (Hill Notation): C12H17N3O4S · H2O
Molecular Weight: 317.36
EC Number: 264-734-5
MDL Number: MFCD09753321
Linear Formula: C12H17N3O4S · H2O
Product Type: Chemical
agency |
traceable to Ph. Eur. I0090000 |
|
traceable to USP 1337809 |
application(s) |
pharmaceutical (small molecule) |
CofA |
current certificate can be downloaded |
form |
solid |
grade |
certified reference material |
|
pharmaceutical secondary standard |
InChI |
1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1 |
InChI key |
GSOSVVULSKVSLQ-JJVRHELESA-N |
packaging |
pkg of 200 mg |
Quality Level |
300 ![External link](https://krackeler.com/images/sigma/ext-link.gif) |
SMILES string |
O.C[C@@H](O)[C@@H]1[C@H]2CC(SCCNC=N)=C(N2C1=O)C(O)=O |
storage temp. |
-10 to -25°C |
technique(s) |
gas chromatography (GC): suitable |
|
HPLC: suitable |
Analysis Note: |
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Application: |
Imipenem may be used as a pharmaceutical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations by various analytical techniques. |
Biochem/physiol Actions: |
Imipenem monohydrate is a broad spectrum B-lactam antibiotic. It is a member of the carbapenem class of "magic bullet" antibiotics for severe infections. |
Footnote: |
To see an example of a Certificate of Analysis for this material enter LRAC0262 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
General description: |
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Imipenem belongs to the class of carbapenems, a beta-lactam antibiotic, effective against aerobic and anaerobic bacteria. Carbapenems act by inhibiting the peptidoglycan synthesis involved in bacterial cell wall formation, thus causing the death of the target microorganism. |
Other Notes: |
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Storage Temp. |
-10 to -25°C |
UNSPSC |
12352200 |