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Linezolid

SIAL/PHR1885 - Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Linezolid; N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; PNU-100766; U-100766

CAS Number: 165800-03-3
Empirical Formula (Hill Notation): C16H20FN3O4
Molecular Weight: 337.35
MDL Number: MFCD00937825
Linear Formula: C16H20FN3O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-PHR1885-500MG 500 mg
 $257.00
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agency traceable to USP 1367561
application(s) pharmaceutical
CofA current certificate can be downloaded
form powder
grade certified reference material
  pharmaceutical secondary standard
InChI 1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
InChI key TYZROVQLWOKYKF-ZDUSSCGKSA-N
packaging pkg of 500 mg
Quality Level 300 
SMILES string CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(N3CCOCC3)c(F)c2
storage temp. 2-8°C
Analysis Note: These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Biochem/physiol Actions: Linezolid is an oxazolidinone antimicrobial. It binds to a site on the bacterial 23S ribosomal RNA of the 50S subunit and prevents the formation of a functional 70S initiation complex, thus inhibiting bacterial mRNA translation. Linezolid is also a weak, reversible, nonselective inhibitor of monoamine oxidase.
Footnote: To see an example of a Certificate of Analysis for this material enter LRAC0768 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
General description: Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Symbol GHS08  GHS08
Signal word Danger
Hazard statements H372
Precautionary statements P260
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 12352200

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