Synonym: Perindopril erbumine; (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt; Perindopril tert-butylamine; S-9490
CAS Number: 107133-36-8
Empirical Formula (Hill Notation): C19H32N2O5 · C4H11N
Molecular Weight: 441.60
MDL Number: MFCD02313824
Linear Formula: C19H32N2O5 · C4H11N
Product Type: Chemical
| agency |
traceable to Ph. Eur. Y0000238 |
| |
traceable to USP 1510889 |
| API family |
perindopril |
| application(s) |
pharmaceutical |
| CofA |
current certificate can be downloaded |
| form |
solid |
| grade |
certified reference material |
| |
pharmaceutical secondary standard |
| InChI |
1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1 |
| InChI key |
IYNMDWMQHSMDDE-MHXJNQAMSA-N |
| packaging |
pkg of 500 mg |
| Quality Level |
300  |
| SMILES string |
CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O)C(=O)OCC |
| storage temp. |
2-8°C |
| Analysis Note: |
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available. |
| Application: |
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Biochem/physiol Actions: |
Perindopril erbumine is an angiotensin converting enzyme (ACE) inhibitor; antihypertensive. |
| Biochem/physiol Actions: |
Perindopril erbumine is an angiotensin converting enzyme (ACE) inhibitor; antihypertensive; becomes hydrolyzed in vivo to the active diacid metabolite; unlike the other ACE inhibitors, inhibits tumor growth in hepatocellular carcinoma cells due to suppression of VEGF levels; also suppresses angiotensin II production in vitro. Long-term therapy with this agent has a beneficial effect on the cerebral circulation by improving cerebral perfusion reserve in patients with previous minor stroke. |
| General description: |
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
| Other Notes: |
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Other Notes: |
To see an example of a Certificate of Analysis for this material enter LRAB0641 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Storage Temp. |
2-8°C |
| UNSPSC |
41116107 |
