Synonym: Perindopril erbumine; (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt; Perindopril tert-butylamine; S-9490
CAS Number: 107133-36-8
Empirical Formula (Hill Notation): C19H32N2O5 · C4H11N
Molecular Weight: 441.60
MDL Number: MFCD02313824
Linear Formula: C19H32N2O5 · C4H11N
Product Type: Chemical
| agency |
traceable to BP 1073 |
| |
traceable to Ph. Eur. Y0000238 |
| |
traceable to USP 1510889 |
| application(s) |
pharmaceutical |
| CofA |
current certificate can be downloaded |
| form |
solid |
| grade |
certified reference material |
| |
pharmaceutical secondary standard |
| InChI |
1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1 |
| InChI key |
IYNMDWMQHSMDDE-MHXJNQAMSA-N |
| packaging |
pkg of 500 mg |
| Quality Level |
300  |
| SMILES string |
CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O)C(=O)OCC |
| storage temp. |
2-8°C |
| Analysis Note: |
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Biochem/physiol Actions: |
Perindopril erbumine is an angiotensin converting enzyme (ACE) inhibitor; antihypertensive; becomes hydrolyzed in vivo to the active diacid metabolite; unlike the other ACE inhibitors, inhibits tumor growth in hepatocellular carcinoma cells due to suppression of VEGF levels; also suppresses angiotensin II production in vitro. Long-term therapy with this agent has a beneficial effect on the cerebral circulation by improving cerebral perfusion reserve in patients with previous minor stroke. |
| Footnote: |
To see an example of a Certificate of Analysis for this material enter LRAB0641 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: |
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
| Other Notes: |
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |
