Synonym: Acetazolamide; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide; N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide; N-(5-[Aminosulfonyl]-1,3,4-thiadiazol-2-yl)acetamide
CAS Number: 59-66-5
Empirical Formula (Hill Notation): C4H6N4O3S2
Molecular Weight: 222.25
EC Number: 200-440-5
MDL Number: MFCD00003105
Linear Formula: C4H6N4O3S2
Product Type: Chemical
agency |
traceable to BP 904 |
|
traceable to Ph. Eur. A0100000 |
|
traceable to USP 1005004 |
application(s) |
pharmaceutical |
CofA |
current certificate can be downloaded |
format |
neat |
grade |
certified reference material |
|
pharmaceutical secondary standard |
InChI |
1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) |
InChI key |
BZKPWHYZMXOIDC-UHFFFAOYSA-N |
packaging |
pkg of 5 g |
Quality Level |
300 ![External link](https://krackeler.com/images/sigma/ext-link.gif) |
SMILES string |
CC(=O)Nc1nnc(s1)S(N)(=O)=O |
storage temp. |
2-30°C |
Analysis Note: |
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Application: |
Carbonic anhydrase inhibitor; increases cerebral blood flow. |
Biochem/physiol Actions: |
Inhibits water permeability of membranes by interacting with aquaporins |
Footnote: |
To see an example of a Certificate of Analysis for this material enter LRAB0911 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
General description: |
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
Other Notes: |
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Symbol |
GHS07 |
Signal word |
Warning |
Hazard statements |
H315 - H319 |
Precautionary statements |
P305 + P351 + P338 |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 2 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Storage Temp. |
2-30°C |
UNSPSC |
12352200 |