Atenolol
SIAL/PHR1909 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Atenolol; (±)
CAS Number: 29122-68-7
Empirical Formula (Hill Notation): C14H22N2O3
Molecular Weight: 266.34
EC Number: 249-451-7
MDL Number: MFCD00057645
Linear Formula: C14H22N2O3
Product Type: Chemical
agency | traceable to BP 492 |
traceable to Ph. Eur. A1340000 | |
traceable to USP 1044403 | |
application(s) | pharmaceutical |
CofA | current certificate can be downloaded |
form | powder |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C14H22N2O3/c1-10(2)16- |
InChI key | METKIMKYRPQLGS-UHFFFAOYSA |
packaging | pkg of 500 mg |
Quality Level | 300 ![]() |
SMILES string | CC(C)NCC(O)COc1ccc(CC(N)= |
storage temp. | 2-30°C |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Application: | This pharmaceutical secondary standard can also be used as follows: • Simultaneous analysis of atenolol and nifedipine using magnesium oxide-nanoplatelets (MgO-NPLs) modified screen-printed electrodes (SPEs) by differential pulse voltammetry (DPV) from pharmaceutical dosage forms and urine samples • Voltammetric determination of amlodipine besylate and atenolol in their combined pharmaceutical formulations using a cathodically pretreated-boron doped diamond electrode (CP-BDDE) • Spectrofluorimetric determination of atenolol using gold nanoparticles (AuNPs) based photo probes in commercial tablets • Amperometric estimation of atenolol using bismuth vanadate-bismuth(III) oxide (BiVO4–Bi2O) composite electrode in pharmaceutical formulations and human urine samples • Development of a reversed phase-high performance liquid chromatography (RP-HPLC) method coupled to a photodiode array detector (PDA) for the quantitative analysis of atenolol and trimetazidine in human urine and pharmaceutical tablets |
Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC0712 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
General description: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Atenolol is a beta-1 blocker used in the treatment of various cardiovascular diseases. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-30°C |
UNSPSC | 12352200 |