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Azacitidine

SIAL/PHR1911 - Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 5-Azacytidine; 4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one; Ladakamycin

CAS Number: 320-67-2
Empirical Formula (Hill Notation): C8H12N4O5
Molecular Weight: 244.20
EC Number: 206-280-2
MDL Number: MFCD00006539
Linear Formula: C8H12N4O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-PHR1911-300MG 300 mg
 $263.00
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agency traceable to USP 1045520
API family azacitidine
application(s) pharmaceutical
CofA current certificate can be downloaded
form powder
grade certified reference material
  pharmaceutical secondary standard
InChI 1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)/t3-,4-,5-,6-/m1/s1
InChI key NMUSYJAQQFHJEW-KVTDHHQDSA-N
mp 226-232 °C (dec.) (lit.)
packaging pkg of 300 mg
Quality Level 300 
SMILES string NC1=NC(=O)N(C=N1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O
storage temp. 2-8°C
Analysis Note: These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application: These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions: A potent growth inhibitor and cytotoxic agent; inhibits DNA methyltransferase, an important regulatory mechanism of gene expression, gene activation and silencing.
Biochem/physiol Actions: Potent growth inhibitor and cytotoxic agent; inhibits DNA methyltransferase.
General description: Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Other Notes: To see an example of a Certificate of Analysis for this material enter LRAB1224 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
mp 226-232 °C (dec.) (lit.)
Storage Temp. 2-8°C
UNSPSC 41116107

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