Lopinavir
SIAL/PHR1927 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Lopinavir
CAS Number: 192725-17-0
Empirical Formula (Hill Notation): C37H48N4O5
Molecular Weight: 628.80
Linear Formula: C37H48N4O5
Product Type: Chemical
agency | BP |
EP | |
traceable to Ph. Eur. Y0001498 | |
traceable to USP 1370101 | |
USP | |
application(s) | pharmaceutical |
biological source | synthetic |
CofA | current certificate can be downloaded |
color | white to off-white |
form | powder |
format | neat |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C37H48N4O5/c1-25(2)34( |
InChI key | KJHKTHWMRKYKJE-SUGCFTRWSA |
mp | 255.2-260.6 °F (124—127°C) |
packaging | pkg of 1 g |
Quality Level | 300 ![]() |
shipped in | ambient |
solubility | chloroform: soluble |
isopropanol: soluble | |
methanol: freely soluble | |
methylene chloride: freely soluble | |
water: practically insoluble | |
storage condition | protect from light |
storage temp. | 2-8°C |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Application: | Lopinavir may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and clinical plasma samples by chromatography techniques. |
Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
Footnote: | To see an example of a Certificate of Analysis for this material enter LRAB1665 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
General description: | Lopinavir is an antiretroviral agent and a protease inhibitor indicated for the management of human immunodeficiency virus (HIV) infection. It is a key component of Kaletra, the co-formulation of lopinavir and ritonavir. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | 255.2-260.6 °F (124—127°C) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |