Synonym: Apigenin; 4′,5,7-Trihydroxyflavone; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone
CAS Number: 520-36-5
Empirical Formula (Hill Notation): C15H10O5
Molecular Weight: 270.24
MDL Number: MFCD00006831
Linear Formula: C15H10O5
Product Type: Chemical
agency |
traceable to USP 1040683 |
CofA |
current certificate can be downloaded |
format |
neat |
grade |
certified reference material |
|
pharmaceutical secondary standard |
InChI |
1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H |
InChI key |
KZNIFHPLKGYRTM-UHFFFAOYSA-N |
mp |
>300 °C (lit.) |
packaging |
pkg of 75 mg |
SMILES string |
Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2 |
storage temp. |
-10 to -25°C |
Analysis Note: |
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Biochem/physiol Actions: |
A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53. Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication. |
Footnote: |
To see an example of a Certificate of Analysis for this material enter LRAC2233 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
General description: |
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
Other Notes: |
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
mp |
>300 °C (lit.) |
Storage Temp. |
-10 to -25°C |
UNSPSC |
41116107 |