Synonym: α-Estradiol; 1,3,5(10)-Estratriene-3,17α-diol; 3,17α-Dihydroxy-1,3,5(10)-estratriene; Epiestradiol
CAS Number: 57-91-0
Empirical Formula (Hill Notation): C18H24O2
Molecular Weight: 272.38
MDL Number: MFCD00064144
Linear Formula: C18H24O2
Product Type: Chemical
CofA |
current certificate can be downloaded |
form |
powder |
grade |
certified reference material |
|
pharmaceutical secondary standard |
InChI |
1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1 |
InChI key |
VOXZDWNPVJITMN-SFFUCWETSA-N |
packaging |
pkg of 50 mg |
SMILES string |
[H][C@]12CC[C@]3(C)[C@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(O)ccc24 |
storage temp. |
2-30°C |
Analysis Note: |
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Biochem/physiol Actions: |
Estradiol (known as alpha Estradiol or 17 alpha Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture.17-estradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke. |
Footnote: |
To see an example of a Certificate of Analysis for this material enter LRAC3407 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
General description: |
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
Other Notes: |
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Storage Temp. |
2-30°C |
UNSPSC |
41116107 |