Menaquinone -7
SIAL/PHR2363 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Vitamin K2-(MK-7); (all-E)
CAS Number: 2124-57-4
Empirical Formula (Hill Notation): C46H64O2
Molecular Weight: 649.00
Linear Formula: C46H64O2
Product Type: Chemical
| agency | traceable to USP 1381119 |
| CofA | current certificate can be downloaded |
| form | solid |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C46H64O2/c1-34(2)18-12 |
| InChI key | RAKQPZMEYJZGPI-LJWNYQGCSA |
| packaging | pkg of 3x75 mg |
| storage temp. | -10 to -25°C |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: | This pharmaceutical secondary standard can also be used as follows:• Ultra high-performance liquid chromatography (UHPLC) based determination of menaquinone-7 and vitamin D3 in their combined tablet formulation • Development of a thin-layer chromatographic-densitome • Simultaneous determination of vitamin D3 and K2 (Menaquinone-4 and Menaquinone-7) in dietary supplements by ultra-high-pressure liquid chromatography (UHPLC) • Impurity profiling of menaquinone-7 in its active pharmaceutical ingredient (API) samples using HPLC coupled to UV detector • Analysis of menaquinone-4 and menaquinone-7 by HPLC in combination with tandem mass spectrometry (MS/MS) in human milk samples |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC4030 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Menaquinone -7 is a naphthoquinone derivative and one of the most active sub-type of vitamin K2, with 7 referring to the number of isoprene units in its structure. It is naturally found in fermented dairy products and is considered a nutrient, thereby being found as a component of various nutritional supplements. |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | -10 to -25°C |
| UNSPSC | 41116107 |