Safinamide Mesylate
SIAL/PHR2379 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Safinamide mesylate salt; (S)
CAS Number: 202825-46-5
Empirical Formula (Hill Notation): C17H19FN2O2 · xCH4O3S
Molecular Weight: 302.34 (free base basis)
MDL Number: MFCD15145475
Linear Formula: C17H19FN2O2 · xCH4O3S
Product Type: Chemical
CofA | current certificate can be downloaded |
form | powder |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C17H19FN2O2.CH4O3S/c1- |
InChI key | YKOCHIUQOBQIAC-YDALLXLXSA |
packaging | pkg of 50 mg |
SMILES string | CS(O)(=O)=O.C[C@H](NCc1cc |
storage temp. | 2-8°C |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Biochem/physiol Actions: | Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, safinamide is voltage-dependent sodium and calcium channel blocker. It appears to bind to the batrachotoxin-sensitive site 2 of the voltage-sensitive sodium channels. Safinamide blocks N and L-type calcium channels and inhibits glutamate and aspartate release from synaptic terminals. |
Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC4350 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
General description: | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Symbol | ![]() ![]() |
Signal word | Warning |
Hazard statements | H302 - H319 - H361d |
Precautionary statements | P202 - P264 - P270 - P301 + P312 - P305 + P351 + P338 - P308 + P313 |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |