Synonym: Palonosetron hydrochloride; (3aS)-2-[(3S)-Quinuclidin-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one hydrochloride; (3aS)-2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-Benz[de]isoquinolin-1-one hydrochloride (1:1); RS 25259-197
CAS Number: 135729-62-3
Empirical Formula (Hill Notation): C19H24N2O · HCl
Molecular Weight: 332.87
MDL Number: MFCD00939524
Linear Formula: C19H24N2O · HCl
Product Type: Chemical
agency |
traceable to USP 1492200 |
CofA |
current certificate can be downloaded |
description |
Pharmaceutical Secondary Standard; Certified Reference Material |
form |
powder |
grade |
certified reference material |
|
pharmaceutical secondary standard |
InChI |
1S/C19H24N2O.ClH/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20;/h2,4,6,13,15,17H,1,3,5,7-12H2;1H/t15-,17-;/m1./s1 |
InChI key |
OLDRWYVIKMSFFB-SSPJITILSA-N |
packaging |
pkg of 200 mg |
SMILES string |
O=C1N([C@H]2C3CCN(CC3)C2)C[C@]4([H])C5=C1C=CC=C5CCC4.[H]Cl |
storage temp. |
2-30°C |
Analysis Note: |
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Biochem/physiol Actions: |
Palonosetron is a potent and selective 5-HT3 receptor antagonist (Aloxi) used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). |
Footnote: |
To see an example of a Certificate of Analysis for this material enter LRAC5931 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
General description: |
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
Other Notes: |
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Symbol |
GHS07 |
Signal word |
Warning |
Hazard statements |
H302 |
Precautionary statements |
P301 + P312 + P330 |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Storage Temp. |
2-30°C |
UNSPSC |
41116107 |