Alpha Lipoic Acid
SIAL/PHR2561
Synonym: (±)-α-Lipoic acid; (±)
CAS Number: 1077-28-7
Empirical Formula (Hill Notation): C8H14O2S2
Molecular Weight: 206.33
MDL Number: MFCD00005474
Linear Formula: C8H14O2S2
Product Type: Chemical
| agency | traceable to Ph. Eur. Y0000546 |
| traceable to USP 1368201 | |
| CofA | current certificate can be downloaded |
| description | Pharmaceutical Secondary Standard; Certified Reference Material |
| form | powder |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C8H14O2S2/c9-8(10)4-2- |
| InChI key | AGBQKNBQESQNJD-UHFFFAOYSA |
| packaging | pkg of 1 g |
| SMILES string | OC(=O)CCCCC1CCSS1 |
| storage temp. | 2-8°C |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Biochem/physiol Actions: | Antioxidant and coenzyme needed for the activity of enzyme complexes such as those of pyruvate dehydrogenase and glycine decarboxylase. Exogenous thioctic acid is reduced intracellularly by two or more enzymes. The reduced form then influences a number of cell processes by direct radical scavenging, recycling of other antioxidants, increasing glutathione synthesis, and modulating transcription factor activity particularly that of NF-κB. Decreases the phagocytosis of myelin by macrophages. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC6145 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Symbol |   GHS07,GHS09 |
| Signal word | Warning |
| Hazard statements | H302 - H315 - H317 - H319 - H411 |
| Precautionary statements | P273 - P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |