Imiquimod
SIAL/PHR2716 - Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 500 mg
Synonym: 1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
CAS Number: 99011-02-6
Empirical Formula (Hill Notation): C14H16N4
Molecular Weight: 240.30
MDL Number: MFCD00866946
Linear Formula: C14H16N4
Product Type: Chemical
agency | traceable to USP 1338313 |
CofA | current certificate can be downloaded |
form | solid |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C14H16N4/c1-9(2)7-18-8 |
InChI key | DOUYETYNHWVLEO-UHFFFAOYSA |
packaging | pkg of 500 mg |
SMILES string | CC(C)Cn1cnc2c(N)nc3ccccc3 |
storage temp. | 2-30°C |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Biochem/physiol Actions: | Imiquimod is a caspase 3 activator, which directly induces procaspase 3 cleavage to active caspase 3. Imiquimod induces apoptosis in vivo in basal cell carcinoma. Its anti-tumor activity is related to the induction of apoptosis. Imiquimod has anti-angiogenic, anti-inflammatory, anti-viral activities. Imiquimod also acts as an immune response modulator inducing the secretion of various cytokines and chemokines. |
General description: | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Symbol | ![]() |
Signal word | Danger |
Hazard statements | H300 - H315 - H319 - H335 |
Precautionary statements | P261 - P264 - P270 - P301 + P310 - P302 + P352 - P305 + P351 + P338 |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-30°C |
UNSPSC | 41116107 |