Tibolone
SIAL/PHR2814 - certified reference material, pharmaceutical secondary standard
Synonym: Tibolone; (7α,17α)-17-Hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one
CAS Number: 5630-53-5
Empirical Formula (Hill Notation): C21H28O2
Molecular Weight: 312.45
Linear Formula: C21H28O2
Product Type: Chemical
agency | traceable to BP |
traceable to Ph. Eur. | |
application(s) | pharmaceutical |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C21H28O2/c1-4-21(23)10 |
InChI key | WZDGZWOAQTVYBX-XOINTXKNSA |
mp | 165-169 °C |
packaging | pkg of 200 mg |
storage temp. | 2-8°C |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
General description: | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
General description: | Tibolone is a synthetic steroid with weak estrogenic, androgenic, and progestogenic activity used in the treatment of menopausal syndrome. Tibolone and its metabolites induce prolactin production in human endometrial stromal cells in vitro. Sulfation plays a major role in the metabolism and regulation of the tissue-specific activity of tibolone and its metabolites. |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H319 |
Precautionary statements | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | 165-169 °C |
Storage Temp. | 2-8°C |